Yang Li, Chief Content Officer of 36Kr: China is gestating a world-class medical company.

Who can cross the confused winter and become the next king of business in the medical and health industry?

Recently, 36Kr WISE2023 "Looking for certainty" King of Business-New Trends of Medical Health was held in Beijing. The conference joined hands with scientists, entrepreneurs and investors to find the "certainty" of the industry worth betting on from the real clinical needs and technological innovation.

Medical health is a track that can cross the cycle and has great development potential. It needs the investment of "1 billion dollars in 10 years" and the hard work of being willing to sit on the bench. At present, China’s basic research ability is booming, and innovative forces are rising. In the great changes, the new generation of enterprises are focusing on the real pain points in clinic, breaking through the technical bottleneck, crossing the market difficulties and risks, step by step, and achieving a win-win situation of social value and commercial value through innovative products and services.

In the opening speech session, Yang Li, chief content officer of 36Kr, mentioned that the number of elderly people over 65 in China has reached 210 million, aging and diseases are issues that must be faced directly, and the market is always calling for medical products and services with real clinical value, which makes everyone firmly believe that the medical and health industry is a trillion-dollar sunrise industry.

She pointed out that in the past, innovative pharmaceutical companies in China seized the opportunity of several super-large targets, which stimulated the expansion of the biomedical industry in China. However, with the maturity of the payer and the capital market, it is difficult to obtain a high premium for the micro-innovation that followed in the past; At present, only the medical instruments that are significantly superior to the original treatment plan in clinical effectiveness and safety can really stand out.

Yang Li, Chief Content Officer of 36Kr

The following is a speech by Ms. Yang Li, Chief Content Officer of 36Kr, edited by 36Kr:

If you are a sci-fi fan, these movies must be familiar.

In The Matrix, human beings in the real world can insert connectors behind their necks and enter the consciousness matrix of the "matrix". In "Avatar", scientists let the brain synchronize with Avatar’s body induction through the induction cabin; In Star Wars, the control of mechanical prostheses through ideas ….. all these vividly depict the super power of brain-computer interface in the future.

This year, Neuralink, Musk’s brain-computer interface company, was officially approved for human clinical trials. Thousands of patients with gradual freezing and spinal cord injury lined up to join the group, hoping to implant electrodes and chips in the brain to regain their motor ability. In China, a number of startups have emerged to develop invasive brain-computer interfaces, which have been favored by investment institutions and are developing more indications. The cutting-edge technological innovation represented by brain-computer interface is the source of vitality of medical and health industry.

Biomedicine is a track with high investment and high risk. However, this year’s popularity of a "magic medicine", Smegrupeptide, has made ordinary people realize how high the return of innovation in pharmaceutical research and development may be. This drug, which was originally used to reduce blood sugar, quickly came out of the circle because of its excellent performance in weight loss. In the first three quarters of 2023 alone, it contributed $14.2 billion to Novo Nordisk. It not only pulls the parent company’s market value beyond LV, but also becomes the current European enterprise market value champion; It also drove the investment boom of the entire GLP-1 receptor agonist track by itself.

The power of science and technology allows human beings to enter outer space, control large models and create billions of wealth. However, in the face of the one-way process of birth, illness and death, human strength is so weak. Up to now, there are still no effective drugs and solutions for common diseases such as nonalcoholic fatty liver and Alzheimer’s disease.

Nowadays, the number of elderly people over 65 in China has reached 210 million. Aging and diseases are issues that must be faced directly. The market is always calling for innovative drugs and medical devices that have real clinical value and can solve pain points. This is what we are willing to firmly believe: the medical and health industry is a trillion-dollar track and a sunrise industry.

However, since the first innovative drug was approved in China in 2011, the development history of innovative drugs in China is only 12 years. Seize the opportunity of several super-large targets, take advantage of local talents and cost advantages, and a number of innovative pharmaceutical companies rose rapidly and rushed to the market, which once stimulated the expansion of the biomedical industry in China.

However, with the maturity of the payer and the capital market, it is difficult to obtain a high premium for the micro-innovation that followed in the past. Only the medical instruments that are significantly superior to the original treatment plan in clinical effectiveness and safety can really stand out.

It is optimistic that China’s basic research ability is booming, and the original innovation ability of biomedicine has also made a qualitative leap, and the whole industrial chain of R&D, design, production and registration supporting innovative medical equipment has also matured. In recent years, China’s innovative drugs and machinery have gradually become a majestic trend, and many enterprises have rushed out of the tight encirclement in the global competition and got a lot of business transcripts.

It can be said that world-class medical companies are being bred in China at present.

Indeed, the phenomenon of "stuck neck" is still common, the trend of medical insurance control fees is still continuing, the enthusiasm of capital has also subsided, and the entrepreneurial game in the pharmaceutical industry has switched to a difficult mode, full of various uncertainties. However, all the guests present are still willing to bend down and enter such a slow but bright track, using medical technology as a spear to overcome stubborn diseases.

The more you are in such a cold winter, the more you need to hold a group to keep warm. Today, we chose a representative medical subdivision track and invited more than 30 entrepreneurs and investors in the frontier medical science and technology field to talk about the inspiration and persistence of medical technology innovation, as well as the uneven road of admission and commercialization.

The fog will eventually disperse, and the winter will eventually pass. The theme of this year’s 36Kr WISE Medical Sub-forum is "Looking for certainty". We hope to sum up the coming 2023, predict the trend of venture capital in the medical and health industry in 2024, and explore more valuable certainty creed. Believe that the sun will eventually rise as usual!

The favorable rate is 98%, and the number one dark horse game in 2023 turned out to be a sewing monster?

Recently, a rhythmic action video game "Hi-Fi RUSH" was directly made into a "King Fried" in the beginning of 2023 without any pre-sale, announcement and trailer, and almost got a 100% favorable rate on the first day of sale on Steam.

Colleagues with bad reviews have also compared their customs clearance speed and level scores in group chat, and Xiaofa has also received many messages from bad friends in the background asking me to talk about this game.

Players who have almost played Hi-Fi RUSH have taken the initiative to become the "tap water" of this game, and some players even commented on this game like this:There is no more rhythmic action game, and there is no more percussion sound tour.

Let’s just say that the position of Hi-Fi RUSH in the game circle at the beginning of the year is almost the position of The Knockout in the hearts of the audience, and it is proper. " Surprise at the beginning of the year "series, not to mention it is also online. If you buy XGP members,You can directly "Bai Piao"!

So today Xiaofa wants to have a good talk with her friends, this fun and top-notch rhythmic action video game "Hi-Fi RUSH".

After entering the game, the whole gameBeautiful painting styleandExtremely high saturationThe game screen caught Xiao Fa’s eye at once. I can say that I have no resistance to this style of game, and I like it almost at first sight.

The plot and story of the game are actually very simple and rude: A tea, a hero with a rolling dream, was implanted with an MP3 in a human experiment, which also led to the identification of A tea as a "defective product" by the robots of the mechanical prosthetic enterprise.

So Acha led a group of music-loving partners and started an uprising revolution against the evil mechanical prosthetic empire.

Although the setting is nothing new, as a "cool tour", simple plot advancement is enough to bring players into the game world.

With an MP3 implanted in her body, everything in Acha’s eyes has become a cyber music world.All the fighting, parkour, jumping, there are traces to follow, and there is a fixed law and rhythm.This setting based on the music card point runs through almost the whole game.

For example, in the process of fighting, if players can play combo according to the rhythm of music, they can play very cool effects and high scores.

In the course of the game, there will be some clever puzzle solving links, which are all related to rhythm and music, such as following BGM to avoid the inspection of infrared rays and jumping rhythmically in the room.

Or turn on the switch to the next level according to a piece of card music.

The elements of music games run through the whole game from the beginning to the end.And the fusion is very clever, and combined with the special effects that appear after the combo, it constantly reminds players that this is a very good music game.

The magical BGM of the whole game allows players to start unconsciously with music during the game.Shake your head and shake your legs.This subconscious conditioned reflex is probably the greatest compliment to a music game.

As for the action game, the whole design of Hi-Fi RUSH is very linear. In this evil mechanical prosthetic factory, Acha needs to keep parkour, find the big BOSS of each level, and then unlock the scene and map of the next BOSS after defeat.

In the process of parkour, you will encounter some small-scale encounters and BOSS battles. After completing these encounters, the game will score the players’ performance in the encounters from several aspects such as your customs clearance speed and combo trigger.

The whole game is inThe design of running map, encounter frequency and puzzle solving is very reasonable.Even let Xiaofa find the coolness and excitement of playing "The Devil May Cry".

Coupled with the elements of music games, Hi-Fi RUSH perfectly combines action games with music games.

This feeling is like a potato meets a large plate of chicken, and a mutton kebab is served with garlic. It may take a little time to get used to it at first, but after playing, you will sigh:They should be made for each other..

And the opening of Hi-Fi RUSH is friendly for novice players, even if your sense of rhythm is poor and you can’t play a perfect combo under ordinary difficulty.Does not affect your customs clearance process., but the score is ugly ~

It gives the player a good tolerance and allows you to adapt slowly.

However, Hi-Fi RUSH also has some shortcomings that Xiaofa personally thinks, first of all, the whole.The novice tutorial is very long., and the wholeThe combo system is very complicatedThere is a relatively high threshold for players to play high-scoring combo and refreshing animation.

In addition, some level designs that need to be stuck still need players to have some understanding.Some music card points are even more difficult than Rhythm in Heaven.This is still a little torture for some players with poor sense of sound.

But on the whole, "Hi-Fi RUSH" is definitely a game work that gives Xiao a very big surprise this year, and it can definitely afford it:There is no more rhythmic action game, no more percussion sound tour,This evaluation.

In fact, after Xiaofa saw the lineup of the production team of Hi-Fi RUSH, he probably understood why this game can have such high quality. Its development team is the Tango Studio of Sanshang Paul under Bethesda Softworks.

And the whole "Resident Evil" series is from the hands of Sanshang Paul ~

Among them, Masaaki Yamada, the chief designer of Hi-Fi RUSH, participated in the production of Resident Evil series, The Devil May Cry and Joy the Red Hero. No wonder Hi-Fi RUSH was dubbed by players as:Musical version of the devil may cry.

It is reasonable that Hi-Fi RUSH can have such game quality.

In fact, this game is more like a game in which several big men in the game circle get together and "want to do something new", so they try a very eccentric music action, but they accidentally make a "cool tour".

So if you like music games, Xiaofa strongly recommends you to start; If you are an action game fan, Xiaofa can also say, " Hi-Fi RUSH won’t let you down, and maybe it will open the door to into the pit Music Tour.

Football scores scouting network-today’s headlines

足球比分球探网

1. "football scores Scouting Network" Li Ruiying, a 57-year-old CCTV female anchor, is so young in recent photos, which is different from her in the news broadcast.

2. The latest news of "football scores scouting network": the poplar radish that choked carmine when willow leaves sprouted.

3, "football scores Scouting Network" and "Moxibustion" make the fetal position incorrect, and the mother avoids caesarean section.

  Nanning, China, 17 September (Reporter Zhang Su) Li Qiang, Prime Minister of the State Council, China, attended the opening ceremony of the 20th China-ASEAN Expo and China-ASEAN Business and Investment Summit in Nanning, Guangxi on the morning of 17 September and delivered a speech. Cambodian Prime Minister Hong Manai, Lao Prime Minister Song Sai, Malaysian Prime Minister Anwar, Vietnamese Prime Minister Fan Mingzheng, Indonesian Vice President Maarouf, Thai Deputy Prime Minister and Minister of Commerce Putan, ASEAN Secretary-General Gao Jinhong, and business representatives from China, ASEAN and other countries and regions attended the meeting.

On the morning of September 17th, Li Qiang, Prime Minister of the State Council, China, attended the opening ceremony of the 20th China-ASEAN Expo and China-ASEAN Business and Investment Summit in Nanning, Guangxi, and delivered a speech. China News Service reporter Yu Jing photo 

  Li Qiang said that the China-ASEAN Expo has witnessed the continuous development of bilateral relations since its establishment 20 years ago. We insist on unity, self-improvement, win-win cooperation, and thinking of the world. China-ASEAN relations have become the most successful and dynamic model in Asia-Pacific regional cooperation and a vivid example of promoting the construction of Community of Shared Future for Mankind.

  李强强调,中国和东盟关系的良好局面来之不易,凝结着各方的共同努力,当中有其本质的内核和贯穿始终的主线,这就是习近平主席精辟概括的“亲、诚、惠、容”四个字。这四个字既是中国周边外交方针的基本取向,也是睦邻友好的相处之道,更是我们共创美好未来的重要法宝。我们要在践行这四个字上下更大功夫,努力营造有利于发展繁荣、和平安宁的良好环境,使各国发展更好惠及周边国家、造福地区人民。

  一是更好地践行“亲”字,进一步深化感情交融。中方愿同东盟扩大文化、旅游、培训、青年等领域合作,不断增进人民相知相亲。二是更好地践行“诚”字,进一步夯实信任根基。中方愿同东盟各国一道,重信守诺开展各领域合作。中国将坚持对外开放的基本国策,努力打造让各国投资者安心放心舒心的良好营商环境。三是更好地践行“惠”字,进一步拉紧利益纽带。中方愿扩大进口东盟国家优势特色产品,不断提升地区互联互通水平,构建更加稳定、畅通、基于比较优势的区域产业链供应链。四是更好地践行“容”字,进一步扩展开放胸襟。中方坚定支持以东盟为中心的区域合作架构,将推动共建“一带一路”倡议同各国发展战略更好对接,持续推进区域经济一体化。

  与会东盟国家领导人在致辞中表示,东盟国家高度赞赏习近平主席提出的亲诚惠容理念,以及中国为促进地区和平与繁荣作出的重要贡献,愿和中方加强合作,进一步开放市场,加强互联互通和相互依存,持续推进共建“一带一路”,增强供应链韧性,反对保护主义和贸易投资政治化,携手应对粮食安全和气候变化等全球性挑战,实现互惠互利、共同发展。

  随后,李强宣布博览会开幕,并与嘉宾共同启幕。

  开幕式后,李强到中国-东盟博览会展馆巡馆,并与参展单位负责人互动交流。

  吴政隆、高云龙出席相关活动。(完)

【编辑:李太源】

The future is set! Guo Ailun was selected into the list of Asian Games, and the fans saw the clue!

The future is set! Guo Ailun was selected into the list of Asian Games, and the fans saw the clue!

Wonderful news! Guo Ailun’s selection for the Asian Games in China Men’s Basketball Team really excited the fans. In the latest list, his name finally appeared, which is undoubtedly an exciting turning point for the fans who felt sorry for missing the China men’s basketball training team coached by Jorjevich because of injury. Looking back on injuries, Guo Ailun missed the China men’s basketball training team because of injuries. However, he didn’t lose heart or shrink back, but actively faced the challenge and insisted on rehabilitation training. He spent a lot of time and energy and went all out to recover. During this time, he faced difficulties with optimism and firmness, and never gave up his vision for the basketball career and the national team. Now, Guo Ailun’s efforts have paid off. He finally won the chance to be selected for the Asian Games list.

He recovered well and was in excellent condition, which showed his brand-new mentality and confidence. Whether in personal training or in communication with teammates, he has shown a positive side. His participation has injected new vitality and confidence into the China men’s basketball team. The fans predicted Guo Ailun’s performance, and thought that he would have an excellent performance in the Asian Games. He has shown extraordinary skills and dominance in domestic leagues for many times. He was once the scoring champion of CBA and had strong scoring and organizational skills. At the same time, he has also made brilliant performances in the international arena, representing China men’s basketball team for many times, showing his strength and potential. Therefore, fans believe that he will once again show his excellent competitive level in the Asian Games.

Guo Ailun’s selection also made fans look forward to the performance of China men’s basketball team in the Asian Games. As an excellent defender, his performance on the court will directly affect the team’s record. As an international event, the Asian Games is extremely competitive, and each team will send its strongest team to compete for honor. In such an environment, Guo Ailun will face the challenges from excellent players from all over the world, but I believe that with his strength and experience, he will be able to cope with it and fight for the honor of the China men’s basketball team. Guo Ailun’s successful selection also makes people have more expectations for his future. The Asian Games is a good opportunity and a platform for him to test his ability. Successful selection into the national team list will also lay a solid foundation for his future basketball career.

Moreover, as a domestic player, Guo Ailun’s success will inspire more young players, set an example for them, and make more people believe that as long as they work hard, they can realize their basketball dreams. To sum up, it is good news that Guo Ailun was selected for the Asian Games of China Men’s Basketball Team. His recovery and positive attitude are admirable, and his outstanding performance in the Asian Games is also expected. I hope he can shine brilliantly in the Asian Games and win glory for the China men’s basketball team. At the same time, we also expect more excellent players like Guo Ailun to show the elegance of China basketball in the international arena and make more contributions to the basketball cause in China. Let’s look forward to cheering for the China Men’s Basketball Team!

Goal net: both the San Luis City and Los Angeles FC teams of the American Professional League are interested in introducing firmino.

Live on March 12th, according to the report of Goal. com, two teams, St. Louis City and Los Angeles FC, of the American Professional League are interested in introducing firmino this summer.

After eight years at Liverpool, 31-year-old firmino will leave the Reds when his contract expires at the end of this season. Before joining Liverpool in 2015, firmino played for Hofenheim for four years. Lutz Pfannenstiel, then head of scouting at Hofenheim, is now Sports director of St. Louis City Club, which may help St. Louis City sign firmino.

(gransabana)